Selected Publications
Ferens, F.G., Summers, W.A., Bharaj, A., Stetefeld, J., Court, D.A. (2021) A C-terminally truncated variant of Neurospora crassa VDAC assembles into a partially functional form in the mitochondrial outer membrane and forms multimers in vitro. Front. Physiol. 12:1441.
Ferens, F.G., Patel, T.R., Oriss, G., Court, D.A., Stetefeld, J. A (2019) A cholesterol analog induces an oligomeric reorganization of VDAC. Biophys J. 116:847-859. (image)
Transporters in mitochondrial inner membranes
Islam, M.D., Harrison, B.D., Li, J.-Y., Court, D.A. (2023) Do mitochondria use efflux pumps to protect their ribosomes from antibiotics? Microbiology 169:001272.
Optimizing phage production
Life in the absence of VDAC, or in the presence of VDAC variants
Shuvo, S.R., Motnenko, A., Krohkin, O.V., Spicer, V., *Court, D.A. (2022) Proteomic shifts reflecting oxidative stress and reduced capacity for protein synthesis, and alterations to mitochondrial membranes in Neurospora crassa lacking VDAC. Microorganisms. 10, 198 (image)
Shuvo, S.R., Wiens, L.M., Subramaniam, S., Treberg, J.R., Court D.A. (2019) Increased reactive oxygen species production and maintenance of membrane potential in VDAC-less Neurospora crassa mitochondria. J. Bioenerg. Biomembr. 51:341-354. (image)
Shuvo, S.R., Kovaltchouk, U., Zubaer, A., Kumar, A., Summers, W.A.T., Donald, L.J., Hausner, G., Court, D.A. (2017) Functional characterization of an N-terminally-truncated mitochondrial porin expressed in Neurospora crassa. Can. J. Microbiol. 63:730-738.
Ferens, F.G., Spicer, V., Krokhin O., Motnenko, A., Summers, W.A.T., Court, D.A. (2017) A deletion variant partially complements a porin-less strain of Neurospora crassa. Bioch. Cell Biol. 95:318-327.
Model of VDAC hexamer in
decylmaltoside/ergosterol micelles
Potential mechanisms of drug efflux from mitochondria
Proteomic changes in the absence of VDAC/porin
ETC changes in the absence of VDAC/porin